Gastrointestinal and hepatic complications of hematopoietic stem cell transplantation

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Pediatric Hematopoietic Stem Cell Transplantation

The introduction and evolution of hematopoietic stem cell transplantation (HSCT) could be traced back to 1950s, to the studies on interactions among irradiation, covering spleen and bone marrow from it and injection of bone marrow cells. Today, HSCT is considered a well-established, effective and promising means of therapy for various malignant and non-malignant medical conditions, both in chil...

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Gastrointestinal Complications Following Hematopoietic Stem Cell Transplantation in Children

Gastrointestinal system involvement is one of the principal complications seen in the recipients of hematopoietic stem cell transplantation (HSCT), and it is also a major cause of morbidity and death in these patients. The major gastrointestinal complications include typhlitis (neutropenic enterocolitis), pseudomembranous enterocolitis, viral enteritis, graft-versus-host disease, benign pneumat...

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Hematopoietic Stem Cell Transplantation for Thalassemia

Thalassemia is an autosomal recessive disorder associated with defective synthesis of the α- or β-chain of hemoglobin. For β-thalassemia major patients, therapeutic options are either monthly red cell transfusions and chelation therapy or allogeneic stem cell transplant. Stem cell transplant is the only curative approach and success is inversely correlated with the degree of iron overload and h...

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Cardiovascular Complications of Hematopoietic Stem Cell Transplantation.

OPINION STATEMENT Survivors of hematopoietic stem cell transplant (HSCT) are at significant risk for cardiac disease and cardiac complications. While there may be cardiac complications during the acute period of HSCT, long-term survivors remain at risk for cardiovascular disease at a rate at least fourfold higher than the general population. Aggressive screening for cardiac risk factors such as...

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Hematopoietic stem cell transplantation (HSCT) has been one of the revolutionary discoveries in the world of science leading to cure of many of the hematological malignancies and for several nonmalignant conditions. It involves harvesting of stem cells from either the bone marrow most traditionally, peripheral blood or umbilical cord and then transplanting them into a recipient [1-3]. This coul...

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ژورنال

عنوان ژورنال: World Journal of Gastroenterology

سال: 2012

ISSN: 1007-9327

DOI: 10.3748/wjg.v18.i16.1851